THE BEST SIDE OF AHU'S

Approximately 80% of TTP is activated by deficient activity of ADAMTS13. ADAMTS13 deficiency could be constitutive, on account of biallelic ADAMTS13 pathogenic variants; or obtained, as a result of an inhibitory antibody. Evaluation of ADAMTS13 activity is carried out using checks based on the aptitude from the protease to cleave common VWF multime